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A new drug approved for weight-loss from the U.S. Food and Drug Administration had achievement in clinical trials, nonetheless it isn't a panacea to lose weight. It must be employed in combination with a low-calorie diet and physical exercise in order to be effective.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the those who go through it one should err assisting caution and let the FDA do its job and demand some investigation be done so the public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on the medications.

Researchers found out that participants using this drug to get a year, dropped excess weight within one month and have kept the load off through the entire 56 weeks from the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which can make them more efficient and safer.

Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that by right now there aren't any long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug could also raise blood pressure levels and heartrate, and really should not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high blood pressure levels, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.


Approving a drug with this many potentially lethal unwanted side effects is inconsistent with all the mission statement from the FDA. The power from the drug manufacturing lobby is blatantly evident inside the approval of countless drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety inside the US.